SGSM1 Antibody (YA1946)
(Synonyms: RUTBC2)SGSM1 Antibody (YA1946) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SGSM1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:200 |
Product Details
SGSM1 Antibody (YA1946) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SGSM1.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 130 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 130 kDa
A synthetic peptide of human SGSM1
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SGSM1 interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as a GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B
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Subcellular Localization
Golgi apparatus, trans-Golgi network; Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasm
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Expression
Tissue_specificity:Mainly expressed in brain, heart and testis -
Isoforms & Post-Translational Modification
Q2NKQ1 has 3 isomers: Q2NKQ1-1: 129718 Da (predicted); Q2NKQ1-3: 132058 Da (predicted); Q2NKQ1-4: 123840 Da (predicted).
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Subunit
Interacts with RAB9A (GTP-bound form) and RAB9B (GTP-bound form); has much lower affinity for GDP-bound RAB9A and RAB9B (PubMed:22637480). Interacts with RAB3A, RAB4A, RAB5A, RAB8A, RAB11A, RAP1A, RAP1B, RAP2A and RAP2B. No interaction with RAB27A (PubMed:17509819)
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SwissProt ID
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Synonyms
RUTBC2
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Research Field
Signal Transduction
Documentation
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