SIVA1 Antibody (YA8258)
(Synonyms: CD27BP; SIVA; Siva-1; Siva-2)SIVA1 Antibody (YA8258) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SIVA1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:150 |
Product Details
SIVA1 Antibody (YA8258) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SIVA1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 18.5 kDa
Full length human recombinant protein of human SIVA1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SIVA1 induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis
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Subcellular Localization
Cytoplasm,Nucleus
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Expression
Tissue_Specificity: Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon -
Isoforms & Post-Translational Modification
O15304 has two isomers: O15304-1: 18695 Da (predicted); O15304-2: 11778 Da (predicted).
Phosphorylated by ABL2/ARG in response to oxidative stress -
Subunit
Binds through its N-terminal region to the C-terminus of CD27 and to PXMP2/PMP22
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SwissProt ID
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Synonyms
CD27BP; SIVA; Siva-1; Siva-2
Documentation
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