SMYD1 Antibody (YA672)
(Synonyms: BOP; KMT3D; ZMYND18; ZMYND22)SMYD1 Antibody (YA672) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SMYD1.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB
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Reactivity :
Rat
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Formulation:
Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Antibody Dilution Buffer (for Western Blot)
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Hematoxylin-Eosin Staining Kit
HY-K0315
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3-Color Prestained Protein Marker (10-190 kDa)
HY-K1011
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Ultra High Sensitivity ECL Kit
HY-K1005
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High Sensitivity ECL Kit
HY-K2005
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Penicillin-Streptomycin (100×), Sterile
HY-K1006
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GelHP Protein Gel (Tris-Gly, 10%, 10 well)
HY-K1111
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DPBS Buffer (1×)
HY-K3008
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GelHP Protein Gel (Tris-Gly, 10%, 15 well)
HY-K1112
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Ponceau Staining Solution (Ready-to-use, 1×)
HY-K1109
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GelHP Protein Gel (Tris-Gly, 12%, 10 well)
HY-K1113
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
SMYD1 Antibody (YA672) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SMYD1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityRat
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Observed Molecular WeightObserved band size: 57 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 57 kDa
Entrez Gene: 297333 Rat
Synthetic peptide corresponding to Human SMYD1.The exact sequence is proprietary to MCE.
Endogenous
affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SMYD1 methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis
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Subcellular Localization
Cytoplasm; Nucleus
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Expression
Tissue_specificity:The expression appears to be primarily limited to the heart and skeletal muscles.
Induction:By serum response factor SRF and myogenin. SRF binds to the CArG site and MYOG binds to the E-box element on SMYD1 promoter -
Subunit
Interacts with HDAC1, HDAC2 and HDAC3. Interacts (via MYND-type zinc finger) with NACA isoform skNAC
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SwissProt ID
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Synonyms
BOP; KMT3D; ZMYND18; ZMYND22
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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