2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. SMYD1 Antibody (YA672)

SMYD1 Antibody (YA672) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SMYD1.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

SMYD1 Antibody (YA672) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SMYD1.
Host

Mouse
Clonality

Monoclonal
Molecular Weight
Predicted band size: 57 kDa;
Observed band size: 57 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Rat
SwissProt ID
Gene ID
Immunogen

Synthetic peptide corresponding to Human SMYD1.The exact sequence is proprietary to MCE.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Purity affinity purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG2b  
Appearance

Liquid
Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis
Subcellular Localization：Cytoplasm; Nucleus
Expression：
Tissue_specificity:The expression appears to be primarily limited to the heart and skeletal muscles.

Induction:By serum response factor SRF and myogenin. SRF binds to the CArG site and MYOG binds to the E-box element on SMYD1 promoter
Subunit：Interacts with HDAC1, HDAC2 and HDAC3. Interacts (via MYND-type zinc finger) with NACA isoform skNAC
Database

Entrez Gene: 297333 Rat

Research Field

Epigenetics and Nuclear Signaling
Synonyms
BOP; KMT3D; ZMYND18; ZMYND22
Documentation
User Guide for Antibodies (1077 KB)

SMYD1 Antibody (YA672) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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SMYD1 Antibody (YA672)
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HY-P80895
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