STAT6 Antibody (YA4011)(PBS only)

Cat. No.: HY-P84314A: Data Sheet User Guide for Antibodies
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STAT6 Antibody (YA4011) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to STAT6.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

STAT6 Antibody (YA4011) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to STAT6.

Host

Mouse

Molecular Weight

Predicted band size: 94 kDa;

Observed band size: 110 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat, Monkey

SwissProt ID

P42226

Gene ID

6778 [NCBI]

Immunogen

Purified recombinant fragment of human STAT6 aa 280-480.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling

Subcellular Localization：Cytoplasm; Nucleus

Isoforms & Post-Translational Modification：P42226 has 3 isomers: P42226-1: 94135 Da (predicted); P42226-2: 74456 Da (predicted); P42226-3: 81748 Da (predicted).
Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4 (PubMed:27796300). Tyrosine phosphorylated following stimulation by IL3/interleukin-3 (By similarity). Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling (PubMed:17210636);Mono-ADP-ribosylated by PARP14

Subunit：Interacts with NCOA1 via its C-terminal LXXLL motif

Synonyms

STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6

Documentation

User Guide for Antibodies (1077 KB)