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Cat. No.: HY-P85510

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TBLR1 Antibody (YA5202)

Name: TBLR1 Antibody (YA5202)
Brand: MedChemExpress
SKU: HY-P85510
Availability: PreOrder

(Synonyms: C21; DC42; F box like/WD repeat containing protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1XR1; FLJ12894; IRA1; Nuclear receptor corepressor/HDAC3 complex subunit; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1 related protein 1; TBL1-related protein 1; TBL1R_HUMAN; TBL1XR1; Transducin; beta; like 1 X linked receptor 1; Transducin beta like 1X related protein 1; Transducin beta-like 1X-related protein 1.)

TBLR1 Antibody (YA5202) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TBLR1.

For research use only. We do not sell to patients.

Host:
Mouse
Application:
WB, IHC-P, ICC/IF
Reactivity :
Human, Mouse

Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Conjugation:
Non-conjugated

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications
Product Details
Product Properties
- Appearance
- Formulation
- Storage & Stability
- Shipping
Background
Documentation
Help & FAQs
Classifications
Bioz

Applications

Application	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence
Dilution Ratio	1:1000	1:200 1:500-1:1000

Product Details

Description

TBLR1 Antibody (YA5202) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TBLR1.

Host Mouse
Clonality Monoclonal
Species Reactivity
Human, Mouse
Observed Molecular Weight

Observed band size: 60 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Immunogen

Purified recombinant human TBLR1 protein fragments expressed in E.coli.

Purification

affinity chromatography.

Conjugation

Non-conjugated

Modification

Unmodified

Product Properties

Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Background

Function

TBLR1 is a F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation
Subcellular Localization

Nucleus
Expression

Tissue_specificity:It is widely expressed in tissues such as the pituitary gland, hypothalamus, white and brown adipose tissue, muscle, and liver.
Subunit

Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1XR1, CORO2A and GPS2 (PubMed:11931768).
SwissProt ID

Q9BZK7
Gene ID

79718 [NCBI]
Synonyms

C21; DC42; F box like/WD repeat containing protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1XR1; FLJ12894; IRA1; Nuclear receptor corepressor/HDAC3 complex subunit; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1 related protein 1; TBL1-related protein 1; TBL1R_HUMAN; TBL1XR1; Transducin; beta; like 1 X linked receptor 1; Transducin beta like 1X related protein 1; Transducin beta-like 1X-related protein 1.