TBX5 Antibody (YA5076)

Cat. No.: HY-P85384: Data Sheet User Guide for Antibodies
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TBX5 Antibody (YA5076) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TBX5.

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사이즈	가격	재고
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

TBX5 Antibody (YA5076) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TBX5.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 58 kDa;

Observed band size: 53 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q99593

Gene ID

6910 [NCBI]

Immunogen

Purified recombinant fragment of TBX5 expressed in E. Coli. The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	Purity	Ascitic Fluid
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in ascitic fluid containing 0.03% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation (PubMed:25725155, PubMed:25963046, PubMed:26917986, PubMed:27035640, PubMed:29174768, PubMed:8988164). Binds to the core DNA motif of NPPA promoter (PubMed:26926761)

Subcellular Localization：Nucleus; Cytoplasm

Isoforms & Post-Translational Modification：Q99593 has 3 isomers: Q99593-1: 57711 Da (predicted); Q99593-2: 39196 Da (predicted); Q99593-3: 52659 Da (predicted).
Acetylation at Lys-339 by KAT2A and KAT2B promotes nuclear retention

Subunit：Monomer (PubMed:20450920). Homodimer (via the T-box); binds DNA as homodimer (PubMed:26926761). Interacts (via the T-box) with NKX2-5 (via the homeobox); this complex binds DNA (PubMed:26926761).

Synonyms

TBX5; T-box transcription factor TBX5; T-box protein 5

각종 서류

User Guide for Antibodies (1077 KB)