TMPRSS4 Antibody (YA9036)
(Synonyms: TMPRSS3, UNQ776/PRO1570, TMPRSS4, Transmembrane protease serine 4, Channel-activating protease 2, Membrane-type serine protease 2, CAPH2, MT-SP2)
Based on 1 Customer Validation
TMPRSS4 Antibody (YA9036) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TMPRSS4.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, ICC/IF, IF-Tissue, IP, ELISA
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Reactivity :
human
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Formulation:
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IP
IP: Immunoprecipitation
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|---|
| Dilution Ratio | 1:100-1000 | 1:50-500 | 1:50-500 | 1-2μg per 100-500μg Total protein | 1:30-3000 |
Product Details
TMPRSS4 Antibody (YA9036) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TMPRSS4.
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Host Mouse
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Species Reactivityhuman
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Calculated Molecular Weight Predicted band size: 48 kDa
OMIM: 606565
A synthesized peptide derived from human TMPRSS4.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at 2-8°C for 1 year, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
TMPRSS4 is a Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC (By similarity)[1].
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Subcellular Localization
Cell membrane
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Expression
Tissue_Specificity: High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract. Coexpressed with ACE2 within mature enterocytes. -
Isoforms & Post-Translational Modification
TMPRSS4 has 4 isoforms, Q9NRS4-1: amino acid length is 437, molecular weight is 48246 Da (predicted); Q9NRS4-2: amino acid length is 432, molecular weight is 47686 Da (predicted); Q9NRS4-3: amino acid length is 435, molecular weight is 48005 Da (predicted); Q9NRS4-4: amino acid length is 397, molecular weight is 43786 Da (predicted).Proteolytically processed; probably by an autocatalytic mechanism
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SwissProt ID
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Synonyms
TMPRSS3, UNQ776/PRO1570, TMPRSS4, Transmembrane protease serine 4, Channel-activating protease 2, Membrane-type serine protease 2, CAPH2, MT-SP2
Documentation
References
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