TNK1 Antibody (YA5084)

Cat. No.: HY-P85392: Data Sheet User Guide for Antibodies
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TNK1 Antibody (YA5084) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TNK1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TNK1 Antibody (YA5084) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TNK1.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 72 kDa;

Species Reactivity

Human

SwissProt ID

Q13470

Gene ID

8711 [NCBI]

Immunogen

Purified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in human tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction

Subcellular Localization：Cytoplasm; Membrane; Peripheral membrane protein

Expression：
Tissue_specificity:Expressed in all umbilical cord blood, bone marrow and human blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in human prostate, testis, ovary, small intestine and colon. Not expressed in human lung, liver, kidney or brain

Isoforms & Post-Translational Modification：Q13470 has 2 isomers: Q13470-1: 72468 Da (predicted); Q13470-2: 71922 Da (predicted).
Autophosphorylated on tyrosine residues

Subunit：Interacts with the SH3 domain of PLCG1 via its Pro-rich domain

Synonyms

TNK1; Non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1

Documentation

User Guide for Antibodies (1077 KB)