TTF-1 Antibody (YA6610)

Cat. No.: HY-P86917: Data Sheet COA
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TTF-1 Antibody (YA6610) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TTF-1.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TTF-1 Antibody (YA6610) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TTF-1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 39 kDa;

Observed band size: 39/42 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P43699

Gene ID

7080 [NCBI]

Immunogen

Recombinant protein within human TTF1 aa 272-371/371.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:4000-1:8000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000-1:5000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:500
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:200-1:500
mIHC mIHC: Multiplex Immunohistochemical	1:4000
IHC-F IHC-F: Immunohistochemistry-Frozen	1:500

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity)

Subcellular Localization：Nucleus

Expression：
Tissue_Specificity: Thyroid and lung

Isoforms & Post-Translational Modification：P43699 has two isomers: P43699-1: 38596 Da (predicted); P43699-3: 41737 Da (predicted).
Phosphorylated on serine residues by STK3/MST2

Subunit：Interacts with WWTR1

Database

SwissProt: P43699 Human ; P50220 Mouse ; P23441 Rat

Synonyms

AV026640 antibody; BCH antibody; Benign chorea antibody; BHC antibody; Homeobox protein NK 2 homolog A antibody; Homeobox protein NK-2 homolog A antibody; Homeobox protein Nkx 2.1 antibody; Homeobox protein Nkx-2.1 antibody; Homeobox protein Nkx2.1 antibody; NK 2 antibody; AV026640 antibody; BCH antibody; Benign chorea antibody; BHC antibody; Homeobox protein NK 2 homolog A antibody; Homeobox protein NK-2 homolog A antibody; Homeobox protein Nkx 2.1 antibody; Homeobox protein Nkx-2.1 antibody; Thyroid transcription factor 1 antibody; Tin man antibody; Tinman antibody; TITF 1 antibody; TITF1 antibody; TTF 1 antibody; TTF-1 antibody; TTF1 antibody

Documentation

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)