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TTF-1 Antibody (YA6610)

(Synonyms: AV026640 antibody; BCH antibody; Benign chorea antibody; BHC antibody; Homeobox protein NK 2 homolog A antibody; Homeobox protein NK-2 homolog A antibody; Homeobox protein Nkx 2.1 antibody; Homeobox protein Nkx-2.1 antibody; Homeobox protein Nkx2.1 antibody; NK 2 antibody; AV026640 antibody; BCH antibody; Benign chorea antibody; BHC antibody; Homeobox protein NK 2 homolog A antibody; Homeobox protein NK-2 homolog A antibody; Homeobox protein Nkx 2.1 antibody; Homeobox protein Nkx-2.1 antibody; Thyroid transcription factor 1 antibody; Tin man antibody; Tinman antibody; TITF 1 antibody; TITF1 antibody; TTF 1 antibody; TTF-1 antibody; TTF1 antibody)
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TTF-1 Antibody (YA6610) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TTF-1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, mIHC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • TTF-1 Antibody (YA6610) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Related Products:
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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
IF-Tissue Info
IF-Tissue: Immunofluorescence-Tissue
mIHC Info
mIHC: Multiplex Immunohistochemical
IHC-F Info
IHC-F: Immunohistochemistry-Frozen
Dilution Ratio 1:4000-1:8000 1:1000-1:5000 1:500 1:200-1:500 1:4000 1:500

Product Details

Description

TTF-1 Antibody (YA6610) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TTF-1.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 39/42 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 39 kDa
Species Reactivity Database
Immunogen

Recombinant protein within human TTF1 aa 272-371/371.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    TTF-1 transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1

  • Subcellular Localization

    Nucleus

  • Expression


    Tissue_Specificity: Thyroid and lung

  • Isoforms & Post-Translational Modification

    P43699 has two isomers: P43699-1: 38596 Da (predicted); P43699-3: 41737 Da (predicted).
    Phosphorylated on serine residues by STK3/MST2

  • Subunit

    Interacts with WWTR1

  • SwissProt ID

    P43699

  • Gene ID
    7080 [NCBI]
  • Synonyms

    AV026640 antibody; BCH antibody; Benign chorea antibody; BHC antibody; Homeobox protein NK 2 homolog A antibody; Homeobox protein NK-2 homolog A antibody; Homeobox protein Nkx 2.1 antibody; Homeobox protein Nkx-2.1 antibody; Homeobox protein Nkx2.1 antibody; NK 2 antibody; AV026640 antibody; BCH antibody; Benign chorea antibody; BHC antibody; Homeobox protein NK 2 homolog A antibody; Homeobox protein NK-2 homolog A antibody; Homeobox protein Nkx 2.1 antibody; Homeobox protein Nkx-2.1 antibody; Thyroid transcription factor 1 antibody; Tin man antibody; Tinman antibody; TITF 1 antibody; TITF1 antibody; TTF 1 antibody; TTF-1 antibody; TTF1 antibody

TTF-1 Antibody (YA6610) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • TTF-1 Antibody (YA6610) Product Image