TUBB2B Antibody (YA8608)
(Synonyms: bA506K6.1; PMGYSA)TUBB2B Antibody (YA8608) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TUBB2B.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
TUBB2B Antibody (YA8608) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TUBB2B.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
Full length human recombinant protein of human TUBB2B produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TUBB2B is a Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Plays a critical role in proper axon guidance in both central and peripheral axon tracts. Implicated in neuronal migration[1][2][3][4].
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Subcellular Localization
Cytoplasm, cytoskeleton
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Expression
Tissue_Specificity: High expression in brain -
Isoforms & Post-Translational Modification
Q9BVA1: 445 amino acids, molecular weight 49953 Da.
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Subunit
Dimer of alpha and beta chains (PubMed:23001566, PubMed:26732629, PubMed:28013290)
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SwissProt ID
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Synonyms
bA506K6.1; PMGYSA
Documentation