TUBB2B Antibody (YA8608)

Cat. No.: HY-P88924: Data Sheet User Guide for Antibodies
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TUBB2B Antibody (YA8608) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TUBB2B.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TUBB2B Antibody (YA8608) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TUBB2B.

Host

Mouse

Clonality

Monoclonal

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9BVA1

Immunogen

Full length human recombinant protein of human TUBB2B produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:23001566, PubMed:26732629, PubMed:28013290). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Plays a critical role in proper axon guidance in both central and peripheral axon tracts (PubMed:23001566). Implicated in neuronal migration (PubMed:19465910)

Subcellular Localization：Cytoplasm, cytoskeleton

Expression：
Tissue_Specificity: High expression in brain

Isoforms & Post-Translational Modification：Q9BVA1: 445 amino acids, molecular weight 49953 Da.

Subunit：Dimer of alpha and beta chains (PubMed:23001566, PubMed:26732629, PubMed:28013290)

Synonyms

bA506K6.1; PMGYSA

Documentation

User Guide for Antibodies (1077 KB)