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UBE2G2 Antibody (YA7892)

(Synonyms: UBC7)

UBE2G2 Antibody (YA7892) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to UBE2G2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P, ICC/IF

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • UBE2G2 Antibody (YA7892) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:150-500 1:100-250

Product Details

Description

UBE2G2 Antibody (YA7892) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to UBE2G2.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 18.4 kDa
Immunogen

Full length human recombinant protein of human UBE2G2 produced in HEK293T cell.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    UBE2G2 is an Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation[1][2][3].

  • Subcellular Localization

    Endoplasmic reticulum,Lipid droplet

  • Isoforms & Post-Translational Modification

    P60604 has two isomers: P60604-1: 18566 Da (predicted); P60604-2: 15614 Da (predicted).

  • Subunit

    Interacts with AUP1 (via C-terminus); the interaction recruits UBE2G2 to lipid droplets (PubMed:21127063, PubMed:21857022, PubMed:23223569)

  • SwissProt ID

    P60604

  • Synonyms

    UBC7

UBE2G2 Antibody (YA7892) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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