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Cat. No.: HY-P87928

Vimentin Antibody (YA7613)

Vimentin Antibody (YA7613) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Vimentin.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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Stock

Quantity

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:1000-1:5000	1:1000-1:5000	1:200-1:1000	1:5000-1:20000

Description

Vimentin Antibody (YA7613) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Vimentin.

Host Rabbit
Clonality Monoclonal,Recombinant
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 54 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 54 kDa

Immunogen

The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

Protein A affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG,Kappa

Appearance

Liquid
Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Vimentin is a Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Plays a role in cell directional movement, orientation, cell sheet organization and Golgi complex polarization at the cell migration front. Protects SCRIB from proteasomal degradation and facilitates its localization to intermediate filaments in a cell contact-mediated manner|Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2
Subcellular Localization

Cytoplasm,Cytoplasm, cytoskeleton,Nucleus matrix,Cell membrane
Expression

Tissue_Specificity: Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines
Induction: Up-regulated by muramyl-dipeptide and lipopolysaccharide
Isoforms & Post-Translational Modification

P08670: 466 amino acids, molecular weight 53652 Da.
Subunit

Homomer assembled from elementary dimers (PubMed:20176112)
SwissProt ID

P08670