APJ receptor agonist 5
APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor (APJ) with an EC50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease.
For research use only. We do not sell to patients.
- CAS No.: 2135514-20-2
- Formula: C26H29N3O6
- Molecular Weight:479.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2135514-20-2
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Molecular Weight 479.52
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Formula C26H29N3O6
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SMILES
CCOCC(N(C1=C(C=CC=C1OC)OC)C(O)=C2C(N3C[C@](C4=CC=CC=C4)([H])CC3)=O)=NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
APJ receptor agonist 5 Related Classifications
HY-145285 Related Classifications
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