TRPV1 antagonist 11
TRPV1 antagonist 11 (compound 2ac) is a potent TRPV1 antagonist with an IC50 of 29.3 nM. TRPV1 antagonist 11 is a potent μ-opioid receptor (MOR) agonist with a Ki of 60.3 nM. TRPV1 antagonist 11, a pyrimidine piperazine, exhibits pain relieving effects by antagonizing TRPV1 and stimulating MOR. TRPV1 antagonist 11 shows a potent, dose-dependent anti-nociceptive effect in a Formalin-induced pain model in mice.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3084843-71-7
- Formel: C31H37N7O2
- Molecular Weight:539.67
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle Opioid Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
TRPV1 29.3 nM (IC50) |
μ Opioid Receptor/MOR 60.3 nM (Ki) |
Chemical Information
-
CAS. Nr. 3084843-71-7
-
Molecular Weight 539.67
-
Formel C31H37N7O2
-
SMILES
COC1=CC2=C(C(CCNC(N3CCN(CC3)C4=NC=CC(N5CCC(CC5)C6=CC=CC=C6)=N4)=O)=CN2)C=C1
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TRPV1 antagonist 11 Related Classifications
HY-176063 Related Classifications
Powered by Bioz