1. Membrane Transporter/Ion Channel
  2. TRP Channel
  3. BI-749327

BI-749327 

Cat. No.: HY-111925
Handling Instructions

BI-749327 is an orally bioavailable TRPC6 antagonist with an IC50 of 13 nM in mice.

For research use only. We do not sell to patients.

BI-749327 Chemical Structure

BI-749327 Chemical Structure

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Description

BI-749327 is an orally bioavailable TRPC6 antagonist with an IC50 of 13 nM in mice[1].

IC50 & Target

IC50: 13 nM (mice TRPC6)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

442.43

Formula

C₂₃H₂₁F₃N₄O₂

SMILES

NC1=NN=C(C2CCN(C(C3=CC=C(OC4=CC=C(C(F)(F)F)C=C4)C=C3)=O)CC2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
BI-749327
Cat. No.:
HY-111925
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BI-749327

Cat. No.: HY-111925