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Cat. No.: HY-134432A

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Boc-Gln-Ala-Arg-AMC hydrochloride

Name: Boc-Gln-Ala-Arg-AMC hydrochloride
Brand: MedChemExpress
SKU: HY-134432A
Availability: PreOrder

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2.

For research use only. We do not sell to patients.

CAS No.: 201849-55-0
Formula: C₂₉H₄₃ClN₈O₈
Molecular Weight:667.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Boc-Gln-Ala-Arg-AMC hydrochloride Chemical Structure

CAS No.: 201849-55-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
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Biological Activity

Description

Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2^[1]^[2].

IC₅₀ & Target

Trypsin^[1]

Chemical Information

CAS No. 201849-55-0
Molecular Weight 667.15
Formula C₂₉H₄₃ClN₈O₈
SMILES

CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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J Chromatogr B Analyt Technol Biomed Life Sci

Identification of potential TMPRSS2 inhibitors via high-throughput screening based on oriented immobilized cell membrane chromatography technology. [Abstract]

2026 Jan 15:1269:124861. PMID: 41265300

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292. [Content Brief]

[2]. Ko CJ, et al. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. Oncogene. 2020 Sep;39(37):5950-5963. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Boc-Gln-Ala-Arg-AMC hydrochloride

1 Cited Publications

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Purity & Documentation
References

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Boc-Gln-Ala-Arg-AMC hydrochloride

Publications Citing Use of MedChemExpress (MCE) Boc-Gln-Ala-Arg-AMC hydrochloride

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

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Boc-Gln-Ala-Arg-AMC hydrochloride Related Classifications

HY-134432A Related Classifications

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