Boc-Gln-Ala-Arg-AMC acetate
Based on 1 publication(s) in Google Scholar
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2.
For research use only. We do not sell to patients.
- Purity: 99.99%
- Formula: C31H46N8O10
- Molecular Weight:690.74
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Publications Citing Use of MedChemExpress (MCE) Boc-Gln-Ala-Arg-AMC acetate
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Biological Activity
Trypsin[1]
Chemical Information
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Appearance Solid
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Molecular Weight 690.74
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Formula C31H46N8O10
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Chromatogr B Analyt Technol Biomed Life Sci
Identification of potential TMPRSS2 inhibitors via high-throughput screening based on oriented immobilized cell membrane chromatography technology. [Abstract]2026 Jan 15:1269:124861. PMID: 41265300
Solvent & Solubility
DMSO : 125 mg/mL (180.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292. [Content Brief]
[2]. Ko CJ, et al. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. Oncogene. 2020 Sep;39(37):5950-5963. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4477 mL | 7.2386 mL | 14.4772 mL | 36.1931 mL |
| 5 mM | 0.2895 mL | 1.4477 mL | 2.8954 mL | 7.2386 mL | |
| 10 mM | 0.1448 mL | 0.7239 mL | 1.4477 mL | 3.6193 mL | |
| 15 mM | 0.0965 mL | 0.4826 mL | 0.9651 mL | 2.4129 mL | |
| 20 mM | 0.0724 mL | 0.3619 mL | 0.7239 mL | 1.8097 mL | |
| 25 mM | 0.0579 mL | 0.2895 mL | 0.5791 mL | 1.4477 mL | |
| 30 mM | 0.0483 mL | 0.2413 mL | 0.4826 mL | 1.2064 mL | |
| 40 mM | 0.0362 mL | 0.1810 mL | 0.3619 mL | 0.9048 mL | |
| 50 mM | 0.0290 mL | 0.1448 mL | 0.2895 mL | 0.7239 mL | |
| 60 mM | 0.0241 mL | 0.1206 mL | 0.2413 mL | 0.6032 mL | |
| 80 mM | 0.0181 mL | 0.0905 mL | 0.1810 mL | 0.4524 mL | |
| 100 mM | 0.0145 mL | 0.0724 mL | 0.1448 mL | 0.3619 mL |