c-Myc inhibitor 8
c-Myc inhibitor 8 (compound 56) is a c-Myc inhibitor. c-Myc inhibitor 8 effectively inhibits cell viability of a variety of cancer cells. c-Myc inhibitor 8 inhibits human prostate and lung cancer growth in mouse models. c-Myc inhibitor 8 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2173505-97-8
- Formula: C19H12BrClF3NO3S2
- Molecular Weight:538.79
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of KU-19-19, 253J, J82, Τ24, ΜΒΤ-2 and UM-UC-3 bladder cancer cell lines with IC50s of 0.90, 1.11, 1.46, 0.98, 1.18 and 1.25 μM, respectively[1]. c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of Α549, NCI-H460, MRC-5 and NCI-H23 hepatoma cell lines with IC50s of 1.70, 1.90, 1.24 and 1.04 μM, respectively[1]. c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of MDA-MB-231, SK-BR-3, HCC1954 and MDA-MB-468 breast cancer cell lines with IC50s of 1.45, 1.38, 1.47 and 1.64 μM, respectively[1]. c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of HL-60, U-937, Raji, Ramos (RAl), Daudi, Jurkat, MV-4-11 and MOLT-4 blood cancer cell lines with IC50s of 1.95, 1.75, 1.12, 1.86, 1.25, 1.06, 1.50 and 1.66 μM, respectively[1]. c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of ΜΙΑ PaCa-2 pancreatic cancer cell line with an IC50 of 1.37 μM[1]. c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of HCT 116, SW620, HCT-15, RKO, HCT-8 and DLD-I colorectal cancer cell lines with IC50s of 1.19, 1.91, 1.32, 1.53, 1.69 and 0.80 μM, respectively[1]. c-Myc inhibitor 8 (0-2 μM; 24 hours) inhibits cell viability of U-251 MG, U-138 MG, LOX-IMVI, SK-HEP-I and OVCAR-3 cancer cell lines with IC50s of 1.17, 1.34, 1.09, 1.02 and 1.09 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2173505-97-8
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Molecular Weight 538.79
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Formula C19H12BrClF3NO3S2
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SMILES
O=C1C2=C(NC(S(CC3=CC=C(C=C3)SC(F)(F)F)=O)=C1C(C)=O)C(Br)=CC=C2Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)