Albendazole-d7
Based on 1 Customer Validation
Albendazole-d7 is the deuterium labeled Albendazole. Albendazole is a broad-spectrum parasiticide with high effectiveness and low host toxicity. Albendazole is used for the research gastrointestinal parasites in humans and animals.
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- CAS No.: 1287076-43-0
- Formule: C12H8D7N3O2S
- Masse moléculaire:272.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1287076-43-0
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Unlabeled Cas 54965-21-8
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Masse moléculaire 272.37
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Formule C12H8D7N3O2S
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SMILES
COC(NC1=NC2=CC(SC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=CC=C2N1)=O
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Synonyms
SKF-62979-d7
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Li L, et al. Determination of albendazole and metabolites in silkworm Bombyx mori hemolymph by ultrafast liquid chromatography tandem triple quadrupole mass spectrometry. PLoS One. 2014;9(9):e105637. Published 2014 Sep 25. [Content Brief]
[3]. Mutavdžić Pavlović D, et al. Sorption of albendazole in sediments and soils: Isotherms and kinetics. Chemosphere. 2018;193:635-644. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)