Carboxybetaine methacrylate
Based on 1 Customer Validation
Carboxybetaine methacrylate is an amphoteric ionic compound with excellent properties such as good hydrophilicity, antistatic property, and biocompatibility. Carboxybetaine methacrylate can be used to prepare tissue engineering scaffolds, drug carriers, and so on.
For research use only. We do not sell to patients.
- Purity: 99.45%
- CAS No.: 24249-95-4
- Formula: C11H19NO4
- Molecular Weight:229.27
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
The GelMA/CBMA hydrogel prepared from Carboxybetaine methacrylate can improve the mechanical properties of gelatin hydrogel, delay the degradation rate, and achieve controlled drug release. Moreover, this hydrogel has good biocompatibility[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 24249-95-4
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Appearance Solid
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Molecular Weight 229.27
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Formula C11H19NO4
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Color White to off-white
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SMILES
O=C(CC[N+](C)(C)CCOC(C(C)=C)=O)[O-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
H2O : 25 mg/mL (109.04 mM; Need ultrasonic)
DMSO : 25 mg/mL (109.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Lai TC , et al. Gelatin methacrylate/carboxybetaine methacrylate hydrogels with tunable crosslinking for controlled drug release. J Mater Chem B. 2016 Apr 7;4(13):2304-2313. [Content Brief]
[2]. Lin W, et al. Different in vitro and in vivo behaviors between Poly(carboxybetaine methacrylate) and poly(sulfobetaine methacrylate). Colloids Surf B Biointerfaces. 2016 Oct 1;146:888-94. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 4.3617 mL | 21.8083 mL | 43.6167 mL | 109.0417 mL |
| 5 mM | 0.8723 mL | 4.3617 mL | 8.7233 mL | 21.8083 mL | |
| 10 mM | 0.4362 mL | 2.1808 mL | 4.3617 mL | 10.9042 mL | |
| 15 mM | 0.2908 mL | 1.4539 mL | 2.9078 mL | 7.2694 mL | |
| 20 mM | 0.2181 mL | 1.0904 mL | 2.1808 mL | 5.4521 mL | |
| 25 mM | 0.1745 mL | 0.8723 mL | 1.7447 mL | 4.3617 mL | |
| 30 mM | 0.1454 mL | 0.7269 mL | 1.4539 mL | 3.6347 mL | |
| 40 mM | 0.1090 mL | 0.5452 mL | 1.0904 mL | 2.7260 mL | |
| 50 mM | 0.0872 mL | 0.4362 mL | 0.8723 mL | 2.1808 mL | |
| 60 mM | 0.0727 mL | 0.3635 mL | 0.7269 mL | 1.8174 mL | |
| 80 mM | 0.0545 mL | 0.2726 mL | 0.5452 mL | 1.3630 mL | |
| 100 mM | 0.0436 mL | 0.2181 mL | 0.4362 mL | 1.0904 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.