1044870-65-6
1044870-65-6
Chemical Structure
MR2938
- CAS No.: 1044870-65-6
- Formula:C21H24N4O3
- Molecular Weight:380.44
IUPAC Name: 5,7-dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)quinazolin-4(3H)-one
InChIKey: RVCUXKFESITCJF-UHFFFAOYSA-N
SMILES: COC1=CC(OC)=C2C(NC(C3=CC=C(C=C3)N4CCN(CC4)C)=NC2=C1)=O
Biological Activity: MR2938 is a potent AChE inhibitor, with an IC50 of 5.04 μM. MR2938 also suppresses NO production obviously (IC50 = 3.29 μM). MR2938 suppresses the neuroinflammation through blocking MAPK/JNK and NF-κB signaling pathways. MR2938 can be used for Alzheimer’s disease (AD) research[1].
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MR2938 | MR2938 is a potent AChE inhibitor, with an IC50 of 5.04 μM. MR2938 also suppresses NO production obviously (IC50 = 3.29 μM). MR2938 suppresses the neuroinflammation through blocking MAPK/JNK and NF-κB signaling pathways. MR2938 can be used for Alzheimer’s disease (AD) research. | |||||||||||||||||||||
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References
Keywords
