1051931-39-5
1051931-39-5
Chemical Structure
ZLJ-6
- CAS No.: 1051931-39-5
- Formula:C13H17N3O6S2
- Molecular Weight:375.42
IUPAC Name: (Z)-2-amino-1-methyl-5-(4-(methylsulfonyl)benzylidene)-1,5-dihydro-4H-imidazol-4-one methanesulfonate
InChIKey: QEJPXTVPNIOEHZ-VEZAGKLZSA-N
SMILES: CS(=O)(O)=O.CN(C(N)=NC/1=O)C1=C/C2=CC=C(C=C2)S(C)(=O)=O
Biological Activity: ZLJ-6 is a dual COX and 5-LOX inhibitor with oral activity. The IC50 values for COX-1, COX-2 and 5-LOX were 0.73, 0.31 and 0.99 μM, respectively. ZLJ-6 has anti-inflammatory and analgesic activity[1][1].
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ZLJ-6 | ZLJ-6 is a dual COX and 5-LOX inhibitor with oral activity. The IC50 values for COX-1, COX-2 and 5-LOX were 0.73, 0.31 and 0.99 μM, respectively. ZLJ-6 has anti-inflammatory and analgesic activity. | |||||||||||||||||||||
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References
Keywords
