1092453-15-0

AZD-8529 Chemical Structure
1092453-15-0

Chemical Structure

AZD-8529

  • CAS No.: 1092453-15-0
  • Formula:C24H24F3N5O3
  • Molecular Weight:487.47

IUPAC Name: 7-methyl-5-(3-(piperazin-1-ylmethyl)-1,2,4-oxadiazol-5-yl)-2-(4-(trifluoromethoxy)benzyl)isoindolin-1-one

InChIKey: IPCYZQQFECEHLI-UHFFFAOYSA-N

SMILES: O=C1C2=C(C)C=C(C3=NC(CN4CCNCC4)=NO3)C=C2CN1CC5=CC=C(OC(F)(F)F)C=C5

Biological Activity: AZD-8529 is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.

Cat. No. Product Name Purity Description Pricing
HY-107457 		AZD-8529 98.17% AZD-8529 is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
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