119897-50-6
119897-50-6
Chemical Structure
2-Deoxy-D-glucose-13C-1
Synonym(s): 2-DG-13C-1;2-Deoxy-D-arabino-hexose-13C-1;D-Arabino-2-deoxyhexose-13C-1
- CAS No.: 119897-50-6
- Formula:C513CH12O5
- Molecular Weight:165.15
IUPAC Name: (3R,4S,5R)-3,4,5,6-tetrahydroxyhexanal-6-13C
InChIKey: VRYALKFFQXWPIH-VOXXIEBZSA-N
SMILES: O=CC[C@@H](O)[C@H](O)[C@H](O)[13CH2]O
Biological Activity: 2-Deoxy-D-glucose-13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
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2-Deoxy-D-glucose-13C-1 | 2-Deoxy-D-glucose-13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | |||||||||||||||||||||
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2-Deoxy-D-glucose-d | 98.0% | 2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | ||||||||||||||||||||
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2-Deoxy-D-glucose-13C | 99.48% | 2-Deoxy-D-glucose-13C is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | ||||||||||||||||||||
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2-Deoxy-D-glucose-13C6 | 2-Deoxy-D-glucose-13C6 (2-DG-13C6) is 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | |||||||||||||||||||||
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2-Deoxy-D-glucose | 99.93% | 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.;Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r [Content Brief]
