2-Deoxy-D-glucose (Standard)
2-Deoxy-D-glucose (Standard) is the analytical standard of 2-Deoxy-D-glucose (HY-13966). This product is intended for research and analytical applications. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexoKinase.
For research use only. We do not sell to patients.
- CAS No.: 154-17-6
- Formula: C6H12O5
- Molecular Weight:164.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 154-17-6
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Molecular Weight 164.16
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Formula C6H12O5
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SMILES
OC1O[C@@H]([C@@H](O)[C@H](O)C1)CO
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Synonyms
2-DG (Standard); 2-Deoxy-D-arabino-hexose (Standard); D-Arabino-2-deoxyhexose (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30. [Content Brief]
[2]. Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in rat skeletal muscle using enzymatic measurement of 2-deoxyglucose 6-phosphate in vitro and in vivo. Biol Signals Recept. 2000 Sep-Oct;9(5):267-74. [Content Brief]
[3]. Miwa H, et al. Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose. Oncol Rep. 2013 May;29(5):2053-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)