1259828-75-5
Chemical Structure
(R)-Pioglitazone-d1
Synonym(s): (R)-U 72107-d1
- CAS No.: 1259828-75-5
- Formula:C19H19DN2O3S
- Molecular Weight:357.44
IUPAC Name: (R)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione-5-d
InChIKey: HYAFETHFCAUJAY-VHLRUQIKSA-N
SMILES: O=C(NC(S1)=O)[C@@]1([2H])CC2=CC=C(C=C2)OCCC3=CC=C(C=N3)CC
Biological Activity: (R)-Pioglitazone-d1 ((R)-U 72107-d1) is a stabilized and deuterated R-enantiomer of pioglitazone, exhibiting pharmacological properties that are beneficial for NASH treatment, including modulation of mitochondrial function, non-steroidal anti-inflammatory effects, and glucose-lowering capabilities.
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(R)-Pioglitazone-d1 | (R)-Pioglitazone-d1 ((R)-U 72107-d1) is a stabilized and deuterated R-enantiomer of pioglitazone, exhibiting pharmacological properties that are beneficial for NASH treatment, including modulation of mitochondrial function, non-steroidal anti-inflammatory effects, and glucose-lowering capabilities. | |||||||||||||||||||||
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(R)-Pioglitazone | (R)-Pioglitazone ((+)-pioglitazone) is the R enantiomer of Pioglitazone (HY-13956). (R)-Pioglitazone is an orally active and selective peroxisome proliferator-activated receptor (PPARγ) agonist with high affinity binding to the PPARγ ligand-binding domain. (R)-Pioglitazone can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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Keywords