1260248-03-0
1260248-03-0
Chemical Structure
AZ3971
- CAS No.: 1260248-03-0
- Formula:C25H22N6O
- Molecular Weight:422.49
IUPAC Name: (S)-5-(4-methoxy-3,5-dimethylphenyl)-5-(3-(pyrimidin-5-yl)phenyl)-5H-pyrrolo[3,4-b]pyrazin-7-amine
InChIKey: BICGYFRWDDPYEI-VWLOTQADSA-N
SMILES: NC1=N[C@](C=2C1=NC=CN2)(C3=CC(C)=C(OC)C(C)=C3)C4=CC(=CC=C4)C=5C=NC=NC5
Biological Activity: AZ3971 is an orally active, blood-brain barrier permeable BACE1 inhibitor that does not affect the activity of γ-secretase. AZ3971 reduces the production of Aβ. AZ3971 can be used for the research of Alzheimer's disease[1].
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AZ3971 | AZ3971 is an orally active, blood-brain barrier permeable BACE1 inhibitor that does not affect the activity of γ-secretase. AZ3971 reduces the production of Aβ. AZ3971 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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References
Keywords
