131559-50-7
Chemical Structure
Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside
- CAS No.: 131559-50-7
- Formula:C39H50O25
- Molecular Weight:918.80
InChIKey: VQNNVXIDBZIDCO-PYKPLJMSSA-N
SMILES: O[C@H]([C@@H](CO[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)O2)[C@H](O)[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)[C@@H]2OC4=C(C5=CC=C(O)C=C5)OC6=CC(O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)=CC(O)=C6C4=O
Biological Activity: Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside is an anti-inflammatory agent. Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside exerts significant anti-inflammatory effects in LPS (HY-D1056)-induced RAW 264.7 macrophages by inhibiting the NF-κB, MAPK and Akt signaling pathways, thereby reducing the production of inflammatory mediators (NO, PGE2) and pro-inflammatory cytokines (TNF-α, IL-1β, IL-6)[1].
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Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside | Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside is an anti-inflammatory agent. Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside exerts significant anti-inflammatory effects in LPS (HY-D1056)-induced RAW 264.7 macrophages by inhibiting the NF-κB, MAPK and Akt signaling pathways, thereby reducing the production of inflammatory mediators (NO, PGE2) and pro-inflammatory cytokines (TNF-α, IL-1β, IL-6). | |||||||||||||||||||||
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