172936-99-1
172936-99-1
Chemical Structure
FR-181877
- CAS No.: 172936-99-1
- Formula:C30H28N2O4
- Molecular Weight:480.55
IUPAC Name: (S)-2-((6-((3-benzhydryl-6-oxopyridazin-1(6H)-yl)methyl)-5,6,7,8-tetrahydronaphthalen-1-yl)oxy)acetic acid
InChIKey: FFRFCEJVGONUHG-NRFANRHFSA-N
SMILES: OC(COC1=C(CC2)C(C[C@H]2CN(C(C=C3)=O)N=C3C(C4=CC=CC=C4)C5=CC=CC=C5)=CC=C1)=O
Biological Activity: FR-181877 (compound 4) is a non-prostaglandin PGI2 agonist. FR-181877 inhibits ADP (HY-W010918)-induced human platelet aggregation with an IC50 value of 0.081 μM[1].
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FR-181877 | FR-181877 (compound 4) is a non-prostaglandin PGI2 agonist. FR-181877 inhibits ADP (HY-W010918)-induced human platelet aggregation with an IC50 value of 0.081 μM. | |||||||||||||||||||||
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Keywords
