1942919-79-0

NVP-BSK805 dihydrochloride Chemical Structure
1942919-79-0

Chemical Structure

NVP-BSK805 dihydrochloride

  • CAS No.: 1942919-79-0
  • Formula:C27H30Cl2F2N6O
  • Molecular Weight:563.47

IUPAC Name: 4-(2,6-difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine dihydrochloride

InChIKey: NUOCAPALWRHKCU-UHFFFAOYSA-N

SMILES: FC1=C(CN2CCOCC2)C(F)=CC(C3=C4N=C(C5=CN(C6CCNCC6)N=C5)C=NC4=CC=C3)=C1.Cl.Cl

Biological Activity: NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-14722A 		NVP-BSK805 dihydrochloride 99.04% NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively.
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