2402779-21-7
Chemical Structure
Sirt1/2-IN-1
- CAS No.: 2402779-21-7
- Formula:C22H13ClN2OS2
- Molecular Weight:420.93
IUPAC Name: 9-chloro-5-(naphthalen-2-yl)-5H-benzo[4,5]thieno[3,2-d]thiazolo[3,2-a]pyrimidin-3(2H)-one
InChIKey: VPROVJRQLOASRW-UHFFFAOYSA-N
SMILES: O=C1CSC2=NC(C3=CC(Cl)=CC=C3S4)=C4C(C5=CC=C6C=CC=CC6=C5)N21
Biological Activity: Sirt1/2-IN-1 (Compound 7) is a SIRT1 and SIRT2 inhibitor with IC50 values of 1.81, 2.10 and 20.5 µg/mL against SIRT1, SIRT2 and SIRT3, respectively. Sirt1/2-IN-1 displays activity in hyperacetylation of α-tubulin protein with an IC50 of 32.05 µg/mL. Sirt1/2-IN-1 shows prominent anticancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Sirt1/2-IN-1 | Sirt1/2-IN-1 (Compound 7) is a SIRT1 and SIRT2 inhibitor with IC50 values of 1.81, 2.10 and 20.5 µg/mL against SIRT1, SIRT2 and SIRT3, respectively. Sirt1/2-IN-1 displays activity in hyperacetylation of α-tubulin protein with an IC50 of 32.05 µg/mL. Sirt1/2-IN-1 shows prominent anticancer activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
