2408342-03-8
Chemical Structure
(S,R,S)-AHPC-Bromooctanoic acid
Synonym(s): VH032-NH-Bromooctanoic acid
- CAS No.: 2408342-03-8
- Formula:C30H43BrN4O4S
- Molecular Weight:635.66
InChIKey: NHAKFEONWVEDRX-ONBPZOJHSA-N
SMILES: BrCCCCCCCC(N[C@@H](C(C)(C)C)C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)=O
Biological Activity: (S,R,S)-AHPC-Bromooctanoic acid is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding linker (HY-W007700). (S,R,S)-AHPC-Bromooctanoic acid can serve as VHL (von Hippel-Lindau) ligand to recruit the VHL protein and serve as a key intermediate for the synthesis of complete PROTAC molecules[1].
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(S,R,S)-AHPC-Bromooctanoic acid | (S,R,S)-AHPC-Bromooctanoic acid is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding linker (HY-W007700). (S,R,S)-AHPC-Bromooctanoic acid can serve as VHL (von Hippel-Lindau) ligand to recruit the VHL protein and serve as a key intermediate for the synthesis of complete PROTAC molecules. | |||||||||||||||||||||
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Keywords
