2413565-19-0
Chemical Structure
COX-2-IN-26
- CAS No.: 2413565-19-0
- Formula:C23H21N7OS3
- Molecular Weight:507.65
IUPAC Name: (E)-2-(((E)-1-((4-(2-(methylthio)-1H-benzo[d]imidazol-1-yl)thiazol-2-yl)amino)propan-2-ylidene)hydrazono)-3-phenylthiazolidin-4-one
InChIKey: LARVQAAGTBVQRP-BOJCHKAJSA-N
SMILES: O=C1N(C2=CC=CC=C2)/C(SC1)=N\N=C(CNC3=NC(N4C(SC)=NC5=C4C=CC=C5)=CS3)/C
Biological Activity: COX-2-IN-26 is a potent, selective and orally active COX-2 inhibitor with IC50 values of 10.61, 0.067, 1.96 µM for COX-1, COX-2, 15-LOX, respectively. COX-2-IN-26 shows anti-inflammatory activity. COX-2-IN-26 shows gastrointestinal safety profile[1].
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COX-2-IN-26 | COX-2-IN-26 is a potent, selective and orally active COX-2 inhibitor with IC50 values of 10.61, 0.067, 1.96 µM for COX-1, COX-2, 15-LOX, respectively. COX-2-IN-26 shows anti-inflammatory activity. COX-2-IN-26 shows gastrointestinal safety profile. | |||||||||||||||||||||
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Keywords
