2568842-57-7
2568842-57-7
Chemical Structure
Flonoltinib sulfate
Synonym(s): JAK2/FLT3-IN-1 sulfate
- CAS No.: 2568842-57-7
- Formula:C25H36FN7O5S
- Molecular Weight:565.66
InChIKey: IEZUCWOITIANPZ-UHFFFAOYSA-N
SMILES: O=S(O)(O)=O.FC1=CC(NC2=NC(C3=CN(C(C)C)N=C3)=C(C)C=N2)=CC=C1N4CCC(CC4)N(CCO)C
Biological Activity: Flonoltinib maleate is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. Flonoltinib maleate has anti-cancer activity[1].
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Flonoltinib sulfate | Flonoltinib maleate is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. Flonoltinib maleate has anti-cancer activity. | |||||||||||||||||||||
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References
Keywords
