2654026-13-6
Chemical Structure
AKT-IN-8
- CAS No.: 2654026-13-6
- Formula:C22H25ClN6O3
- Molecular Weight:456.93
IUPAC Name: (4aS,6R)-6-amino-N-((S)-1-(4-chlorophenyl)-3-hydroxypropyl)-4,4a,5,6,7,8-hexahydro-9H-3-oxa-1,8a,9,11-tetraazadibenzo[cd,f]azulene-6-carboxamide
InChIKey: AWLFPOHXSPBHQB-PONJGIIJSA-N
SMILES: OCC[C@@H](C1=CC=C(C=C1)Cl)NC([C@@]2(C[C@]3([H])N(CC2)C4=C5C(OC3)=CN=C5N=CN4)N)=O
Biological Activity: AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively[1].
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AKT-IN-8 | AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively. | |||||||||||||||||||||
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Keywords