2714434-41-8

YAP/TAZ-TEAD-IN-3 Chemical Structure
2714434-41-8

Chemical Structure

YAP/TAZ-TEAD-IN-3

  • CAS No.: 2714434-41-8
  • Formula:C24H21ClF2N2O3
  • Molecular Weight:458.88

InChIKey: RUJIOLXLDFOAMK-MCFWBGNESA-N

SMILES: O=C(C1=[C@@]([C@@]2=C3[C@H](C)[C@](C4=CC=CC=C4)(CN)OC3=CC(F)=C2Cl)C(F)=C(OC)C=C1)N

Biological Activity: YAP/TAZ-TEAD-IN-3 is a YAP/TAZ-TEAD interaction inhibitor with an IC50 of 1.8 nM. YAP/TAZ-TEAD-IN-3 can be used as a TEAD1 ligand to construct PROTACs, such as PROTAC TEAD degrader-2 (HY-186021)[1].

Cat. No. Product Name Purity Description Pricing
HY-186022 		YAP/TAZ-TEAD-IN-3 YAP/TAZ-TEAD-IN-3 is a YAP/TAZ-TEAD interaction inhibitor with an IC50 of 1.8 nM. YAP/TAZ-TEAD-IN-3 can be used as a TEAD1 ligand to construct PROTACs, such as PROTAC TEAD degrader-2 (HY-186021).
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