YAP/TAZ-TEAD-IN-3
YAP/TAZ-TEAD-IN-3 is a YAP/TAZ-TEAD interaction inhibitor with an IC50 of 1.8 nM. YAP/TAZ-TEAD-IN-3 can be used as a TEAD1 ligand to construct PROTACs, such as PROTAC TEAD degrader-2 (HY-186021).
For research use only. We do not sell to patients.
- CAS No.: 2714434-41-8
- Formula: C24H21ClF2N2O3
- Molecular Weight:458.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All YAP Isoforms
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Biological Activity
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YAP/TAZ-TEAD 1.8 nM (IC50) |
TEAD1 |
Chemical Information
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CAS No. 2714434-41-8
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Molecular Weight 458.88
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Formula C24H21ClF2N2O3
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SMILES
O=C(C1=[C@@]([C@@]2=C3[C@H](C)[C@](C4=CC=CC=C4)(CN)OC3=CC(F)=C2Cl)C(F)=C(OC)C=C1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)