2765997-88-2
2765997-88-2
Chemical Structure
CDK4/6-IN-21 maleate
- CAS No.: 2765997-88-2
- Formula:C31H34F2N8O4
- Molecular Weight:620.65
InChIKey: QCKCFHAHQYPXKS-BTJKTKAUSA-N
SMILES: OC(/C=C\C(O)=O)=O.CC(N(C1CC1)C2=CC(C3=NC(NC4=CC=C(CN(CC5)CCN(C)C)C5=N4)=NC=C3F)=C6)=NC2=C6F
Biological Activity: CDK4/6-IN-21 maleate (compound I-52) is a CDK4/6 inhibitor with IC50 values of 3.88 and 3.31 nM for CDK4 and CDK6, respectively. CDK4/6-IN-21 maleate has antitumor activity[1].
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CDK4/6-IN-21 maleate | CDK4/6-IN-21 maleate (compound I-52) is a CDK4/6 inhibitor with IC50 values of 3.88 and 3.31 nM for CDK4 and CDK6, respectively. CDK4/6-IN-21 maleate has antitumor activity. | |||||||||||||||||||||
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References
Keywords
