CDK4/6-IN-21 maleate
CDK4/6-IN-21 maleate (compound I-52) is a CDK4/6 inhibitor with IC50 values of 3.88 and 3.31 nM for CDK4 and CDK6, respectively. CDK4/6-IN-21 maleate has antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 2765997-88-2
- Formula: C31H34F2N8O4
- Molecular Weight:620.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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CDK4 3.88 nM (IC50) |
CDK6 3.31 nM (IC50) |
Chemical Information
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CAS No. 2765997-88-2
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Molecular Weight 620.65
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Formula C31H34F2N8O4
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SMILES
OC(/C=C\C(O)=O)=O.CC(N(C1CC1)C2=CC(C3=NC(NC4=CC=C(CN(CC5)CCN(C)C)C5=N4)=NC=C3F)=C6)=NC2=C6F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)