2803837-13-8
Chemical Structure
CDK2/4/6-IN-1
- CAS No.: 2803837-13-8
- Formula:C22H22N4O4S
- Molecular Weight:438.50
IUPAC Name: 6-ethynyl-8-((1R,2R)-2-hydroxy-2-methylcyclopentyl)-2-((4-(methylsulfonyl)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
InChIKey: XTZONGZKZYDCAY-XMSQKQJNSA-N
SMILES: O=S(C1=CC=C(NC2=NC=C3C(N([C@@H]4CCC[C@]4(O)C)C(C(C#C)=C3)=O)=N2)C=C1)(C)=O
Biological Activity: CDK2/4/6-IN-1(example 29) is a CDK2/4/6 inhibitor with IC50 values of 2.5, 23.7 and 44.3 nM for CDK2, CDK4 and CDK6, respectively. CDK2/4/6-IN-1 can be used in cancer research[1]. CDK2/4/6-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CDK2/4/6-IN-1 | CDK2/4/6-IN-1(example 29) is a CDK2/4/6 inhibitor with IC50 values of 2.5, 23.7 and 44.3 nM for CDK2, CDK4 and CDK6, respectively. CDK2/4/6-IN-1 can be used in cancer research. CDK2/4/6-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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Keywords
