2883496-10-2
Chemical Structure
HIV-1 inhibitor-53
- CAS No.: 2883496-10-2
- Formula:C30H34N2O8S
- Molecular Weight:582.66
IUPAC Name: 5,6-dihydroxy-N-((2S,3R)-3-hydroxy-4-((N-isobutyl-4-methoxyphenyl)sulfonamido)-1-phenylbutan-2-yl)benzofuran-2-carboxamide
InChIKey: LESPNRYBKODRHR-RPLLCQBOSA-N
SMILES: COC1=CC=C(C=C1)S(=O)(N(C[C@H]([C@@H](NC(C2=CC3=C(O2)C=C(C(O)=C3)O)=O)CC4=CC=CC=C4)O)CC(C)C)=O
Biological Activity: HIV-1 inhibitor-53 is a dual HIV-1 protease and reverse transcriptase inhibitor. HIV-1 inhibitor-53 inhibits HIV-1 protease (PR) and reverse transcriptase (RT) activity with IC50 values of 1.93 nM and 2.35 μM, respectively. HIV-1 inhibitor-53 can be used for the research of acquired immune deficiency syndrome (AIDS)[1].
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HIV-1 inhibitor-53 | HIV-1 inhibitor-53 is a dual HIV-1 protease and reverse transcriptase inhibitor. HIV-1 inhibitor-53 inhibits HIV-1 protease (PR) and reverse transcriptase (RT) activity with IC50 values of 1.93 nM and 2.35 μM, respectively. HIV-1 inhibitor-53 can be used for the research of acquired immune deficiency syndrome (AIDS). | |||||||||||||||||||||
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Keywords
