3026272-26-1
Chemical Structure
Seladelpar sodium
Synonym(s): MBX-8025 sodium; RWJ-800025 sodium
- CAS No.: 3026272-26-1
- Formula:C21H22F3NaO5S
- Molecular Weight:466.45
IUPAC Name: sodium (R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetate
InChIKey: XCAXFCPCOXDEHC-UNTBIKODSA-M
SMILES: O=C(O[Na])COC1=CC=C(SC[C@H](OCC)COC2=CC=C(C(F)(F)F)C=C2)C=C1C
Biological Activity: Seladelpar (MBX-8025) sodium salt is an orally active, potent and specific PPARδ agonist with an EC50 of 2 nM. Seladelpar sodium salt shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar sodium salt hydrochloride can be used for the study of primary biliary cholangitis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Seladelpar sodium | 98.59% | Seladelpar (MBX-8025) sodium salt is an orally active, potent and specific PPARδ agonist with an EC50 of 2 nM. Seladelpar sodium salt shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar sodium salt hydrochloride can be used for the study of primary biliary cholangitis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
