3051587-93-7
Chemical Structure
CDK2-IN-44
- CAS No.: 3051587-93-7
- Formula:C21H27F2N5O3S
- Molecular Weight:467.53
InChIKey: NUWDCQVOANFVQE-UHFFFAOYSA-N
SMILES: FC1=CC(C2=NC(NC3CCN(S(=O)(C4CC4)=O)CC3)=NC=C2F)=CN(C(CC)C)C1=O
Biological Activity: CDK2-IN-44 (Compound 46) is an inhibitor of cyclin-dependent kinase 2 (CDK2). CDK2-IN-44 can effectively inhibit the proliferation of cancer cells and exert its activity in inhibiting cancer cell growth by arresting the cell cycle, promoting Apoptosis, and inducing cellular senescence. CDK2-IN-44 holds promise for use in the research of ovarian cancer and breast cancer[1].
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CDK2-IN-44 | CDK2-IN-44 (Compound 46) is an inhibitor of cyclin-dependent kinase 2 (CDK2). CDK2-IN-44 can effectively inhibit the proliferation of cancer cells and exert its activity in inhibiting cancer cell growth by arresting the cell cycle, promoting Apoptosis, and inducing cellular senescence. CDK2-IN-44 holds promise for use in the research of ovarian cancer and breast cancer. | |||||||||||||||||||||
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Keywords