CDK2-IN-44
CDK2-IN-44 (Compound 46) is an inhibitor of cyclin-dependent kinase 2 (CDK2). CDK2-IN-44 can effectively inhibit the proliferation of cancer cells and exert its activity in inhibiting cancer cell growth by arresting the cell cycle, promoting Apoptosis, and inducing cellular senescence. CDK2-IN-44 holds promise for use in the research of ovarian cancer and breast cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 3051587-93-7
- 화학식: C21H27F2N5O3S
- 분자량:467.53
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
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CDK2 |
Chemical Information
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CAS No. 3051587-93-7
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분자량 467.53
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화학식 C21H27F2N5O3S
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SMILES
FC1=CC(C2=NC(NC3CCN(S(=O)(C4CC4)=O)CC3)=NC=C2F)=CN(C(CC)C)C1=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Hot Topics
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Topics
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Topics Cellular Senescence & Age-related Diseases
Cellular senescence is a stable state of cell-cycle arrest triggered by diverse forms of cellular stress, including telomere shortening, DNA damage, oncogene activation, mitochondrial dysfunction, oxidative stress, and chromatin perturbation.
2026-06-18
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Topics Senolytics and Senomorphic Strategies in Aging Research
Cellular senescence is a stable state of cell-cycle arrest triggered by DNA damage, telomere attrition, oncogenic signaling, and other forms of cellular stress.
2026-06-18
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Topics Molecular Spark of cGAS-STING-Mediated Cellular Senescence
Cellular senescence is a stress-response program characterized by irreversible cell-cycle arrest and the senescence-associated secretory phenotype (SASP), originally recognized as a tumor-suppressive mechanism and now considered a central process in aging biology, inflammation, and cancer research.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)