3126891-54-8
Chemical Structure
HDAC6-IN-77
- CAS No.: 3126891-54-8
- Formula:C17H16ClFN2O2
- Molecular Weight:334.77
InChIKey: DDWPUQFTNAAEHN-UHFFFAOYSA-N
SMILES: ClC1=CC=C(CCN(CC2=CC=C(C(NO)=O)C=C2F)C3)C3=C1
Biological Activity: HDAC6-IN-77 is a highly selective HDAC6 inhibitor with an IC50 of 7.0 nM.HDAC6-IN-77 induces neurite outgrowth.HDAC6-IN-77 exerts neuroprotective activity.HDAC6-IN-77 shows no significant toxicity on dopaminergic cells.HDAC6-IN-77 can be used for the research of Alzheimer's disease[1].
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HDAC6-IN-77 | HDAC6-IN-77 is a highly selective HDAC6 inhibitor with an IC50 of 7.0 nM.HDAC6-IN-77 induces neurite outgrowth.HDAC6-IN-77 exerts neuroprotective activity.HDAC6-IN-77 shows no significant toxicity on dopaminergic cells.HDAC6-IN-77 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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Keywords