Cav 3.2 inhibitor 1
Cav 3.2 inhibitor 1 is a T-type calcium channel inhibitor with little binding affinity to dopamine D2 receptors. Cav 3.2 inhibitor 1 can be used for the research of somatic and visceral pain.
For research use only. We do not sell to patients.
- CAS No.: 2878598-59-3
- Formula: C32H39N3O
- Molecular Weight:481.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Calcium Channel Isoforms
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Biological Activity
Cav 3.2[1]
Cav 3.2 inhibitor 1 (compound 3a, 0.3 μM) inhibits Cav3.2 activities by about 50% in Cav3.2-transfected HEK293 cells[1].
Cav 3.2 inhibitor 1 (1 and 10 μM) displays little binding affinity to D2 receptors[1].
Cav 3.2 inhibitor 1 (0.01-1 μM) inhibits T-currents in Cav3.1-expressing HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Cav 3.2 inhibitor 1 (8 nmol/mouse, i.c.v.) has no effect on long-lasting catalepsy in mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Colonic pain and referred hyperalgesia mice induced by intracolonic (i.col.) administration of Na2S at 5 nmol/mouse[1].
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Dosage:1-10 mg/kg
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Administration:Intraperitoneal injection (i.p.)
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Result:Completely blocked the Na2S-induced colonic pain and referred hyperalgesia.
Chemical Information
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CAS No. 2878598-59-3
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Molecular Weight 481.67
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Formula C32H39N3O
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SMILES
O=C1N(CCCCC2=CC=CC=C2)C3=CC=CC=C3N1C4CCN(CCCCC5=CC=CC=C5)CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cav 3.2 inhibitor 1 Related Classifications
HY-151450 Related Classifications
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