2. Metabolic Enzyme/Protease
  3. Angiotensin-converting Enzyme (ACE)
  4. CGS 35601

CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats.

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CGS 35601

CGS 35601 화학구조

CAS No. : 849066-09-7

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CGS 35601 Related Antibodies

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제품 설명

CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats[1].

IC50 & Target

IC50: 55 nM (ECE-1), 2 nM (NEP), 22 nM (ACE)
분자량

445.58

화학식

C23H31N3O4S
CAS No.
SMILES

CC(C)C[C@H](S)C(NC1(CCCC1)C(N[C@@H](CC2=CNC3=C2C=CC=C3)C(O)=O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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  • Do most proteins show cross-species activity?

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Keywords:

CGS 35601849066-09-7CGS35601CGS-35601Angiotensin-converting Enzyme (ACE)Sprague Dawley’s ratSD rathypertensionheart failureCGS 37808Inhibitorinhibitorinhibit

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상품명:
CGS 35601
Cat. No.:
HY-18211
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