15(S)-HETE
Based on 1 Customer Validation
15(S)-HETE is an endogenous metabolite present in Urine that can be used for the research of Zellweger Syndrome.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.0%
- CAS. Nr.: 54845-95-3
- Formel: C20H32O3
- Molecular Weight:320.47
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Speicherung:
Solution, -20°C, 2 years
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
7.3 μM
Compound: 1
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Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
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[PMID: 3806609] |
| RBL-1 | IC50 |
7.3 μM
Compound: 15-HETE
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In vitro inhibitory activity against RBL-1 5-LO
In vitro inhibitory activity against RBL-1 5-LO
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[PMID: 3820229] |
In Vitro
Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 54845-95-3
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Appearance Liquid
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Molecular Weight 320.47
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Formel C20H32O3
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Color Colorless to light yellow
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SMILES
CCCCC[C@H](O)/C=C/C=C\C/C=C\C/C=C\CCCC(O)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Solution, -20°C, 2 years
Reinheit & Dokumentation
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Data Sheet (261 KB)
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SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [Content Brief]
[2]. Mayatepek E, et al. 12- and 15-hydroxyeicosatetraenoic acid are excreted in the urine of peroxisome-deficient patients: evidence for peroxisomal metabolism in vivo. Pediatr Res. 1996 Jan;39(1):146-9. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
15(S)-HETE Related Classifications
HY-113336 Related Classifications
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