Salicortin
Salicortin, a phenolic glycoside, has been isolated from many plants such as Populus and Salix species. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Salicortin has anti-amnesic, anti-adipogenic, and immune-modulatory activity.
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- CAS. Nr.: 1887055-63-1
- Formel: C20H24O10
- Molecular Weight:424.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
JNK |
NF-κB |
In Vitro
Salicortin (100 μM; 2 hours) almost completely retards the phosphorylation of IκBα[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Mouse bone marrow macrophage (BMM)
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Concentration:100 μM
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Incubation Time:2 hours
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Result:Retarded the phosphorylation of IκBα.
Chemical Information
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CAS. Nr. 1887055-63-1
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Molecular Weight 424.40
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Formel C20H24O10
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SMILES
O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC=CC=C2COC([C@]3(O)C=CCCC3=O)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Salicortin Related Classifications
HY-123503 Related Classifications
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