PARP14 inhibitor 2
PARP14 inhibitor 2 (Compound 3) is an orally active and highly selective PARP14 inhibitor with an IC50 value of <30 nM. PARP14 inhibitor 2 inhibits the mono-ADP-ribosyltransferase activity of PARP14 and regulates IFN-γ and IL-4 signaling, reversing protumor macrophage polarization and inhibiting anti-tumor inflammatory responses. PARP14 inhibitor 2 is promising for research of PARP14-related diseases such as tumors, atopic dermatitis and autoimmune diseases.
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- CAS No.: 3064731-00-3
- Formule: C25H32FN3O4S
- Masse moléculaire:489.60
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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PARP14 <30 nM (IC50) |
Chemical Information
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CAS No. 3064731-00-3
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Masse moléculaire 489.60
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Formule C25H32FN3O4S
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SMILES
O=C1N=C(CSC2CCOCC2)NC3=CC(OCC45CCC(CC4)(CC5)NC(C)=O)=CC(F)=C13
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PARP14 inhibitor 2 Related Classifications
HY-176456 Related Classifications
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